Bioinformatics approaches to analyzing CRISPR screen data: from dropout screens to single-cell CRISPR screens.

Quantitative Biology（2022）

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摘要

Different analysis approaches should be chosen based on the design of screens. This review will help community to better design novel algorithms and provide suggestions for wet-lab researchers to choose from different analysis methods.

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关键词

CRISPR/Cas9,dropout screen,drug-gene interaction,single-cell CRISPR screen,sorting-based screen

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