Effects of Trimetazidine on Right Ventricular Function and Ventricular Remodeling in Patients with Pulmonary Artery Hypertension: A Randomised Controlled Trial.

Hugo E Verdejo, Adolfo Rojas,Camila López-Crisosto,Fernando Baraona,Luigi Gabrielli,Vinicius Maracaja-Coutinho,Mario Chiong,Sergio Lavandero,Pablo F Castro

Journal of clinical medicine（2023）

引用 5|浏览14

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摘要

A short course of trimetazidine is safe and well-tolerated on PAH patients, and it is associated with significant increases in the 6MWT and minor but significant improvement in RV remodeling. The therapeutic potential of this drug should be evaluated in larger clinical trials.

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关键词

6 min walk test,fatty acid beta-oxidation inhibitor,pro-BNP,pulmonary artery hypertension,right ventricular failure,trimetazidine

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