Systemic inflammatory regulators and proliferative diabetic retinopathy: A bidirectional Mendelian randomization study.

Qiqin Shi,Qiangsheng Wang,Zhenqian Wang,Jiawen Lu,Ruobing Wang

Frontiers in immunology（2023）

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摘要

Our MR study identified two upstream regulators and six downstream effectors of PDR, providing opportunities for new therapeutic exploitation of PDR onset. Nonetheless, these nominal associations of systemic inflammatory regulators and PDR require validation in larger cohorts.

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关键词

Mendelian randomization,bidirectional,meta-analysis,proliferative diabetic retinopathy,systemic inflammatory regulators

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