Tissue optical clearing for neural regeneration research

Nerve injury,whether traumatic or degenerative,disrupts the transmission of information in the nervous system,leading to dysfunction.It is widely known that neural regeneration is vital to the restoration of function after nerve injury.Still,outcomes are often limited by the misguidance of axonal regeneration and complex pathological changes in neurons and glia,as well as the long-term denervation of target organs.Morphological analyses of neural tissues and target organs are vital for outcome assessments in neural regeneration research.