P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis.

Titilope M Dokunmu,Sandra C Opara,Ngozi Awa Imaga,Omiete U Awani,David O Enoma,Bababode I Adelani

Asian Pacific journal of cancer prevention : APJCP（2023）

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摘要

This study shows a dose-dependent synergistic anticancer effects of caffeine and artemisinin combination on p53 gene and nitric oxide regulation hence can mitigate tumor development.

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关键词

Artemisinin,Cancer Prevention,DMBA,caffeine,tumor suppressor gene

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