The inhibitory effect of 6-gingerol and cisplatin on ovarian cancer and antitumor activity: In silico , in vitro , and in vivo .

Zohreh Salari,Ahmad Khosravi, Elham Pourkhandani,Elaheh Molaakbari,Ehsan Salarkia,Alireza Keyhani,Iraj Sharifi,Hadi Tavakkoli,Samira Sohbati,Shahriar Dabiri,Guogang Ren,Mohammad Shafie'ei

Frontiers in Oncology（2023）

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摘要

The findings of the present study demonstrated that the cisplatin and 6-gingerol combination is more effective in inducing apoptosis and suppressing the angiogenesis of ovarian cancer cells than using each drug alone.

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关键词

angiogenesis,apoptosis,chick embryo,cisplatin,gingerol,molecular dynamics simulation,ovarian neoplasm

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