Self-supervised contrastive learning using CT images for PD-1/PD-L1 expression prediction in hepatocellular carcinoma.

Tianshu Xie,Yi Wei,Lifeng Xu,Qian Li,Feng Che,Qing Xu,Xuan Cheng,Minghui Liu,Meiyi Yang,Xiaomin Wang,Feng Zhang,Bin Song,Ming Liu

Frontiers in Oncology（2023）

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摘要

We demonstrated that a non-invasive deep learning-based model trained with self-supervised contrastive learning could accurately predict the PD-1 and PD-L1 expression status, and might assist the precision treatment of patients withHCC, in particular the use of immune checkpoint inhibitors.

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关键词

PD-1/L1,computed tomography,contrastive learning,deep learning,hepatocellular carcinoma,self-supervised learning

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