Two New Sesquiterpenoids from Kalimeris shimadae

Five sesquiterpenoids were isolated from Kalimeris shimadae, of which compounds 1 and 2 were undescribed guaiane-type and eudesmane-type sesquiterpenoids, named kalshinoids G (1) and H (2). Their structures and relative configurations were elucidated based on HR-MS, NMR and chemical calculations. The inhibitory activity of those sesquiterpenes against nitric oxide (NO) production were also evaluated.