HUCMSC-derived Exosomes Suppress the Titanium Particles-induced Osteolysis in Mice through Inhibiting CCL2 and CCL3.

Shixun Li,Chuangran Wu,Sipeng Lin,Zhenkang Wen,Wenqiang Luo,Changchuan Li,Xiaoyan Wang, Xuejia Li,Liangbin Gao,Yue Ding

Orthopaedic surgery（2023）

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摘要

HUCMSCs and HUCMSC-derived exosomes could suppress the titanium particles-induced osteolysis in mice through inhibiting chemokine (C-C motif) ligand 2, chemokine (C-C motif) ligand 3.

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关键词

Aseptic loosening,CCL2,CCL3,Exosome,HUCMSC,Macrophage

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