Infarcted Myocardium Calls for T-Cell Help to Regulate Repair

Circulation Research(2023)

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HomeCirculation ResearchVol. 132, No. 5Infarcted Myocardium Calls for T-Cell Help to Regulate Repair No AccessEditorialRequest AccessFull TextAboutView Full TextView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toNo AccessEditorialRequest AccessFull TextInfarcted Myocardium Calls for T-Cell Help to Regulate Repair Xudong Li and Pilar Alcaide Xudong LiXudong Li Department of Immunology, Tufts University School of Medicine, Boston, MA. Search for more papers by this author and Pilar AlcaidePilar Alcaide Correspondence to: Pilar Alcaide, PhD, Department of Immunology, Tufts University School of Medicine, 136 Harrison Ave, M&V 701, Boston, MA 02111. Email E-mail Address: [email protected] https://orcid.org/0000-0003-3013-3982 Department of Immunology, Tufts University School of Medicine, Boston, MA. Search for more papers by this author Originally published2 Mar 2023https://doi.org/10.1161/CIRCRESAHA.123.322556Circulation Research. 2023;132:583–585This article is a commentary on the followingMyocardial Milieu Favors Local Differentiation of Regulatory T Cellsis related toIn this IssueFootnotesFor Sources of Funding and Disclosures, see page 585.The opinions expressed in this article are not necessarily those of the editors or of the American Heart Association.Correspondence to: Pilar Alcaide, PhD, Department of Immunology, Tufts University School of Medicine, 136 Harrison Ave, M&V 701, Boston, MA 02111. Email pilar.[email protected]eduReferences1. Prabhu SD, Frangogiannis NG. The biological basis for cardiac repair after myocardial infarction: from inflammation to fibrosis.Circ Res. 2016; 119:91–112. doi: 10.1161/CIRCRESAHA.116.303577LinkGoogle Scholar2. Gagliani N, Amezcua Vesely MC, Iseppon A, Brockmann L, Xu H, Palm NW, de Zoete MR, Licona-Limon P, Paiva RS, Ching T, et al. 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A unique population of regulatory T cells in heart potentiates cardiac protection from myocardial infarction.Circulation. 2020; 142:1956–1973. doi: 10.1161/CIRCULATIONAHA.120.046789LinkGoogle Scholar12. Kanamori M, Nakatsukasa H, Okada M, Lu Q, Yoshimura A. Induced regulatory T cells: their development, stability, and applications.Trends Immunol. 2016; 37:803–811. doi: 10.1016/j.it.2016.08.012CrossrefMedlineGoogle Scholar13. Li X, Zheng Y. Regulatory T cell identity: formation and maintenance.Trends Immunol. 2015; 36:344–353. doi: 10.1016/j.it.2015.04.006CrossrefMedlineGoogle Scholar14. Feng Y, Arvey A, Chinen T, van der Veeken J, Gasteiger G, Rudensky AY. Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus.Cell. 2014; 158:749–763. doi: 10.1016/j.cell.2014.07.031CrossrefMedlineGoogle Scholar15. Li X, Liang Y, LeBlanc M, Benner C, Zheng Y. Function of a Foxp3 cis-element in protecting regulatory T cell identity.Cell. 2014; 158:734–748. doi: 10.1016/j.cell.2014.07.030CrossrefMedlineGoogle Scholar eLetters(0)eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are not peer-reviewed. Acceptable comments are posted to the journal website only. Comments are not published in an issue and are not indexed in PubMed. Comments should be no longer than 500 words and will only be posted online. References are limited to 10. Authors of the article cited in the comment will be invited to reply, as appropriate.Comments and feedback on AHA/ASA Scientific Statements and Guidelines should be directed to the AHA/ASA Manuscript Oversight Committee via its Correspondence page.Sign In to Submit a Response to This Article Previous Back to top Next FiguresReferencesRelatedDetailsRelated articlesMyocardial Milieu Favors Local Differentiation of Regulatory T CellsMurilo Delgobo, et al. Circulation Research. 2023;132:565-582In this IssueCirculation Research. 2023;132:541-541 March 3, 2023Vol 132, Issue 5 Advertisement Article InformationMetrics © 2023 American Heart Association, Inc.https://doi.org/10.1161/CIRCRESAHA.123.322556PMID: 36862810 Originally publishedMarch 2, 2023 KeywordsEditorialischemiamyocardiumcell deathheart diseaseregulatoryT-lymphocytesPDF download Advertisement
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infarcted myocardium,repair,t-cell
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