Hypereosinophilic syndrome in Europe: Retrospective study of treatment patterns, clinical manifestations, and healthcare resource utilization.

Jeremiah Hwee,Lynn Huynh,Shawn Du,Namhee Kwon,Rupert W Jakes,Rafael Alfonso-Cristancho,Lee Baylis,Gema Requena,Anamika Khanal,Marc E Rothenberg,Mei Sheng Duh

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology（2023）

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摘要

Patients with HES across 5 European countries had a substantial disease burden despite extensive oral corticosteroids treatment, highlighting the need for additional targeted therapies.

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关键词

COPD: chronic obstructive pulmonary disease,CRSwNP: chronic rhinosinusitis with nasal polyps,CT: computed tomography,ER: emergency room,GDPR: general data protection regulation,HCRU: healthcare resource utilization,HES: hypereosinophilic syndrome,IL-5: interleukin-5,IQR: interquartile range,KM: Kaplan−Meier,MRI: magnetic resonance imaging,OCS: oral corticosteroids,RMST: restricted mean survival time,SD: standard deviation,UK: United Kingdom,US: United States,eCRF: electronic case report form,healthcare resource utilization, corticosteroids, hypereosinophilic syndrome, clinical manifestation, flare, biologics, immunosuppressants, treatment patterns, Europe Abbreviations/Acronyms: CI: confidence interval

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