The impact of transmembrane 6 superfamily 2 (TM6SF2) rs58542926 on liver-related events in patients with advanced chronic liver disease.

Lorenz Balcar,Bernhard Scheiner,Markus Urheu,Patrick Weinberger,Rafael Paternostro,Benedikt Simbrunner,Georg Semmler,Claudia Willheim,Matthias Pinter,Peter Ferenci,Michael Trauner,Thomas Reiberger,Albert Friedrich Stättermayer,Mattias Mandorfer

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver（2023）

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摘要

The TM6SF2 variant modulates liver disease progression beyond the development of ACLD, as it modifies the risks of hepatic decompensation and liver-related death, independently of baseline liver disease severity.

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关键词

Cirrhosis,Decompensation,Genetics,Liver fibrosis,Portal hypertension

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