Structural studies put phage defense mystery on the RADAR.

Timothy Wiryaman,Ian J MacRae

Cell(2023)

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摘要
Phage restriction by adenosine deaminase acting on RNA (RADAR) is a process by which bacteria may alter their own transcriptome to resist bacteriophage. In this issue of Cell, Duncan-Lowey and Tal et al. and Gao et al. both show RADAR proteins assemble into massive molecular complexes but present distinct views about how these assemblies obstruct phage.
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关键词
phage defense mystery,structural studies
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