Factors associated with the humoral response after three doses of COVID-19 vaccination in kidney transplant recipients.

Ángel Bulnes-Ramos,María Mar Pozo-Balado,Israel Olivas-Martínez,Vanesa Garrido-Rodríguez, Gabriel Bernal-Blanco,Alejandro Suárez-Benjumea,Ana Isabel Álvarez-Ríos,Carmen Lozano,Carmen González-Corvillo,Marta Suñer-Poblet,Francisco Manuel González-Roncero,Berta Sánchez,Isabel Maldonado-Calzado, José Manuel Lara-Ruiz,María Francisca Gonzalez-Escribano,Yolanda María Pacheco

Frontiers in immunology（2023）

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摘要

In addition to the immunosuppression therapy, condition of kidney function and age before vaccination, specific immune factors could also be relevant in light of optimization of the COVID-19 vaccination protocol in KTR. Therefore, thymosin-a1, an immunomodulatory hormone, deserves further research as a potential adjuvant for the next vaccine boosters.

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关键词

COVID-19,kidney transplant,mRNA vaccine,relative telomere length,sj/β-TREC ratio,thymic function,thymosin-α1

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