Integrative genetic and single cell RNA sequencing analysis provides new clues to the amyotrophic lateral sclerosis neurodegeneration.

Frontiers in neuroscience（2023）

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摘要

These cellular similarities and differences deepened our understanding of the heterogeneous cellular basis of ALS, SA, HMN, SPG, and SMA.

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关键词

amyotrophic lateral sclerosis (ALS),genome-wide association studies (GWAS),motor neurons (MNs),neurological disorder,single-cell transcriptome

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