Myopia control in Mendelian forms of myopia.

Emilie van der Sande,Jan Roelof Polling,J Willem L Tideman,Magda A Meester-Smoor,Alberta A H J Thiadens,Emily Tan,Chris I De Zeeuw, Ralph Hamelink,Ingo Willuhn,Virginie J M Verhoeven,Beerend H J Winkelman,Caroline C W Klaver

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)（2023）

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摘要

High-dose atropine had the same effect on AL in high myopic children with and without a known monogenetic cause. In mice featuring a severe form of Mendelian myopia, atropine reduced AL progression. This suggests that atropine can reduce myopia progression even in the presence of a strong monogenic driver.

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关键词

Mendelian myopia,atropine,dopamine,lipoprotein receptor-related protein 2 knockout mouse,myopia control,syndromic myopia

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