谷歌浏览器插件
订阅小程序
在清言上使用

Acute Myocarditis with Transient Myocardial Thickening in Two Oncologic Patients Treated with Anti‐gd2 Immunotherapy

ESC heart failure(2023)

引用 0|浏览15
暂无评分
摘要
Immunotherapy has considerably improved clinical outcomes in different types of cancers but has also been associated with the development of myocarditis, especially with that mediated by immune checkpoint inhibitors. To the best of our knowledge, these are the first cases of myocarditis after anti-GD2 immunotherapy reported to date. We present two cases of paediatric patients who, after anti-GD2 infusion, presented severe myocarditis with myocardial hypertrophy detected on echocardiography and confirmed with cardiac magnetic resonance imaging. An increase in myocardial T1 and extracellular volume of up to 30% was observed with heterogeneous intramyocardial late enhancement. Myocarditis after anti-GD2 immunotherapy may be more common than appreciated, occurs early after starting treatment, has a malignant course, and responds to higher steroid doses.
更多
查看译文
关键词
Myocarditis,Immunotherapy,Cardiac magnetic resonance imaging,Corticosteroids
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要