Polypyrrole enwrapped binary metal oxides nanostructures for in-vitro Dopamine detection from lacrimal fluid

•Synthesis, characterization and biosensing application of polypyrrole enwrapped nanoparticles.•The redox active sites of Fe2O3 created passage for electron transportation.•La2O3 induced massive defects for DA adsorption.•PPy provided stability and enhanced electron shuttling.•These synergistic properties amplified the transduction signals leading to the higher electrocatalytic activity for DA oxidation.