Determining Combined Modality Dosimetric Constraints by Integration of IMRT and LDR Prostate Brachytherapy Dosimetry and Correlation with Toxicity.

Adam C Riegel,Jason D Nosrati,Baho U Sidiqi, Ann Cooney, Yen-Ruh Wuu,Lucille Lee,Louis Potters

Advances in radiation oncology（2023）

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摘要

We successfully applied our dose integration technique to a sample of patients with intermediate- and high-risk prostate cancer. Incidence of grade 3 toxicity was low, suggesting that combined doses observed in this study were safe. We suggest preliminary dose constraints as a conservative starting point to investigate and escalate prospectively in a future study.

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关键词

ldr prostate brachytherapy dosimetry,combined modality dosimetric constraints,toxicity

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