TMT quantitative proteomics and network pharmacology reveal the mechanism by which asiaticoside regulates the JAK2/STAT3 signaling pathway to inhibit peritoneal fibrosis.

Journal of ethnopharmacology（2023）

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摘要

ASI can inhibit PMCs MMT and alleviate PF by regulating the JAK2/STAT3 signaling pathway.

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关键词

Asiaticoside,JAK2/STAT3 signaling pathway,Mesothelial-mesenchymal transition,Network pharmacology,Peritoneal mesothelial cells,Proteomics

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