Preoperative hydronephrosis is an independent protective factor of renal function decline after nephroureterectomy for upper tract urothelial carcinoma.
Frontiers in oncology（2023）
摘要
Pre-NU hydronephrosis is an independent protective predictor for post-NU RF decline, CKD progression, and eligibility for adjuvant therapy. With cautious selection for those unfavorably prognostic, non-metastatic UTUC patients with preoperative hydronephrosis, adjuvant rather than neoadjuvant therapy could be considered due to higher chance of preserving eligibility.
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关键词
adjuvant therapy,chronic kidney disease,cisplatin-based chemotherapy,hydronephrosis,immune-oncology therapy,nephroureterectomy,renal function,upper tract urothelial carcinoma
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