Prostaglandin E 2 Production by Brain Endothelial Cells and the Generation of Fever.

DNA and cell biology（2023）

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摘要

We recently demonstrated that prostaglandin production in brain endothelial cells is both necessary and sufficient for the generation of fever during systemic immune challenge. I here discuss this finding in light of the previous literature and point to some unresolved issues.

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关键词

Slco1c1 promoter,cyclooxygenase-2,intravenous,lipopolysaccharide,mice,microsomal prostaglandin E synthase-1

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