Deep palmar phenotyping in atopic eczema: patterns associated with Filaggrin variants, disease severity and barrier function in a South Asian population.

Bjorn R Thomas,Xiang Li Tan,Stefan Van Duijvenboden,Sarah C Hogan,Aaron J Hughes,Soha S Tawfik,Sasha Dhoat,Ravinder Atkar,Elizabeth J Robinson,Syedia R Rahman,Samiha Rahman, Rehana A Ahmed,Rubina Begum, Habiba Khanam, Emma L Bourne,Eva L Wozniak,Charles A Mein,David P Kelsell,Edel A O'Toole

The British journal of dermatology（2023）

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摘要

Palm patterns associate with EASI and TEWL. The fine perpendicular/prominent diamond patterns are markers to detect absence/presence of LoF FLG variants respectively.

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