Differences between HbA1c and glucose-related variables in predicting weight loss and glycaemic changes in individuals with overweight and hyperglycaemia – The PREVIEW trial

Marta P Silvestre,Mikael Fogelholm,Marta Alves,Ana Papoila,Tanja Adam,Amy Liu,Jennie Brand-Miller,J. Alfredo Martinez,Margriet Westerterp-Plantenga,Teodora Handjieva-Darlenska,Ian A. Macdonald,Ruixin Zhu,Elli Jalo,Roslyn Muirhead,Santiago Navas Carretero,Svetoslav Handjiev,Moira A. Taylor,Anne Raben,Sally D. Poppitt

Clinical nutrition (Edinburgh, Scotland)（2023）

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摘要

Whilst neither HbA nor fasting glucose predicts short-term weight loss success, both may impact the metabolic response to rapid weight loss. We propose a role of inflammation versus total body adiposity since these variables are independent predictors of the normalisation of HbA and fasting glucose, respectively.

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关键词

Hemoglobin A(1c),Impaired fasting glucose,Impaired glucose tolerance,Prediabetes,Weight loss/ reduction

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