Deep brain stimulation improves central nervous system inflammation in Parkinson's disease: Evidence and perspectives.

CNS neuroscience & therapeutics(2023)

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摘要
The results of this study indicate that PD patients have a persistent inflammatory profile, possibly via recruitment of activated monocytes, macrophages, and T lymphocytes to the central nervous system (CNS). DBS was shown to have a significant therapeutic effect on PD, which may arise by improving the inflammatory environment of the central nervous system.
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关键词
Parkinson's disease,RANTES,TNF-α,deep brain stimulation,immunological disturbances,inflammation
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