Biocompatibility analysis of halloysite clay nanotubes

Giuseppe Lazzara,Francesca Bruno,Desiree Brancato,Valentina Sturiale, Agata Grazia D'Amico, Stefana Miloto,Pooria Pasbakhsh,Velia D'Agata,Salvatore Saccone,Concetta Federico

Materials Letters（2023）

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摘要

•Halloysite clay nanotubes HNT-N,-U,-P,-S were analyzed by in vitro cell tests.•MTT and CBMN assays were used to test HNTs cellular and genomic toxicity.•HNTs, with the in vitro test on mammalian cells, showed a good biocompatibility.•Only at the highest concentrations HNTs showed a moderate level of toxicity.•Caution is suggested for future use of large amounts of HNTs on human applications.

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关键词

Genotoxic assay,Cytotoxic assay,Nanotechnology,Halloysite,Nanotubes

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