Metabolic and Inflammatory profiles define phenotypes with clinical relevance in female knee osteoarthritis patients with joint effusion.

Joan Calvet,María García-Manrique,Antoni Berenguer-Llergo,Cristóbal Orellana,Silvia Garcia Cirera,Maria Llop,Carlos Galisteo Lencastre,Marta Arévalo,Cristina Aymerich,Rafael Gómez,Néstor Albiñana Giménez,Jordi Gratacó

Rheumatology (Oxford, England)（2023）

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摘要

Our results support the existence of different KOA phenotypes with clinical relevance and differing pathways regarding their pathophysiology and disease evolution, which entails implications in patients' stratification, treatment tailoring and the search of novel and personalized therapies.

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关键词

Knee osteoarthritis,clinical severity,inflammatory,machine learning,metabolism,phenotype

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