Fungal Osler Nodes Indicate Candidal Infective Endocarditis.

Fungal infective endocarditis is rare, and diagnostic tests such as blood cultures and echocardiography may not detect the disease.• The mortality rate of fungal endocarditis is high, with improved clinical outcomes if diagnosed and treated early.• Clinicopathologic correlation between integumentary examination and skin biopsy findings may provide timely diagnosis, thereby guiding appropriate therapy.