Single-cell RNA sequencing reveals the role of cell heterogeneity in the sex difference in primary hyperparathyroidism.
Frontiers in endocrinology(2023)
摘要
These findings suggest that the sex difference in PHPT may be caused by the differentially expressed genes and activated pathways in different cell types in the parathyroid tissue. The heterogeneity of parathyroid cell subpopulations, especially in oxyphil cells, may be associated with the sex differences in PHPT pathogenesis.
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关键词
ScRNA-seq,cellular interactions,gene expression,primary hyperparathyroidism,sex difference
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