Immune tolerance breakdown in inborn errors of immunity: Paving the way to novel therapeutic approaches.

Giuliana Giardino,Roberta Romano,Vassilios Lougaris,Riccardo Castagnoli,Francesca Cillo,Lucia Leonardi,Francesco La Torre,Annarosa Soresina,Silvia Federici,Caterina Cancrini,Lucia Pacillo,Elisabetta Toriello,Bianca Laura Cinicola,Stefania Corrente,Stefano Volpi,Gian Luigi Marseglia,Claudio Pignata,Fabio Cardinale

Clinical immunology (Orlando, Fla.)（2023）

引用 0|浏览30

暂无评分

摘要

Up to 25% of the patients with inborn errors of immunity (IEI) also exhibit immunodysregulatory features. The association of immune dysregulation and immunodeficiency may be explained by different mechanisms. The understanding of mechanisms underlying immune dysregulation in IEI has paved the way for the development of targeted treatments. In this review article, we will summarize the mechanisms of immune tolerance breakdown and the targeted therapeutic approaches to immune dysregulation in IEI.

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要