Supplementary Figures 1 Through 11 and Supplementary Figure and Video Legends from Modeling Spontaneous Metastasis Following Surgery: an in Vivo-In Silico Approach

Supplementary Figure 1. In vitro fit and direct statistical analysis of the xenograft breast data. Supplementary Figure 2. Population fit of the tumor growth data. Supplementary Figure 3. Population fits of the breast xenograft data under different growth theories. Supplementary Figure 4. Population fits of the kidney isograft data under different growth theories. Supplementary Figure 5. Second kidney data set used for fitting the data (resection time = 23 days). Supplementary Figure 6. Individual fits of primary tumor and metastatic burden kinetics. Supplementary Figure 7. Individual fits of primary tumor and metastatic burden kinetics. Supplementary Figure 8. Link between experimental and model survival. Supplementary Figure 9: Surgery benefit on survival and metastatic burden reduction as a function of resection size, for varying values of metastatic potential. Supplementary Figure 10. Population fits of the ortho-surgical metastasis animal models. Supplementary Figure 11. Population fits of the ortho-surgical metastasis animal models.