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One-pot Synthesis of 2,6-Diaryl-4,5-dihydropyridazin-3(2h)-ones: Copper Catalyzed Annulation of Aldehydes, Arylhydrazines and 3-Acryloyloxazolidin-2-one

Jianbo Zhao, Shengshu Lei,Min Wu, Can Pang,Hao Li

TETRAHEDRON LETTERS（2023）

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Abstract
•The three-component starting materials are available aldehydes, arylhydrazines and 3-acryloyloxazolidin-2-one.•This strategy exhibits high tolerance towards many functional aldehydes.•The useful tetrahydropyridazines could be achieved in excellent yields by one-step reduction.
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Key words
Annulation,Copper,One-pot,Pyridazinones
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