Supplementary Tables 1 - 5, Figure 1 from Drug–Gene Modeling in Pediatric T-Cell Acute Lymphoblastic Leukemia Highlights Importance of 6-Mercaptopurine for Outcome

PDF file - 266K, Table S1 - Top 50 Correlating Probes For Each Drug Used in the 10 Drug Model. Table S2 - Drug-Gene Correlations for Genes Associated with Canonical Pathways of Multi-Drug Resistance, Detoxification and Metabolism (light shading p<0.01, dark shading with bold p<0.001). Table S3 -Details of Ingenuity Pathway Analysis for Individual Drugs, Drug Pairs, Genes of the 10 Drug Model, and the GC-MTX Reciprocity Index (data represent p-value and number of molecules (#) associated with significant sub-pathways). Table S4. Ten Drug Model Prediction Accuracies Across Different Cohorts Table S5 - Logistic Regression Models Used to Predict Patient Outcome in Each T-ALL Cohort. Figure S1 - Resistant Subgroups Within (A) POG-8704 and (B) POG-9404 Cohorts