Supplementary Methods and Figures 1 - 6 from Systemic Delivery of <i>Salmonella typhimurium</i> Transformed with IDO shRNA Enhances Intratumoral Vector Colonization and Suppresses Tumor Growth

PDF file - 221K, Supplemental Figs: 1. Transformation of VNP20009 with shIDO does not enhance its infectivity 2. ShIDO-ST reduces the formation of melanoma lung metastases. 3. Frequency of Gr1+CD11b+ cells in organs of tumor-bearig mice receiving PBS, shScr-ST, or shIDO-ST treatment. 4. Apoptotic CD45+ subsets in tumors of shIDO-ST treated mice includes CD4+ and CD8+ cells. 5. Hypoxia alone does not induce apoptosis in shIDO-ST-infected B16F10 cells. 6. ShIDO-ST treatment suppresses subcutaneous (s.c.) Pan02 tumor growth in C57BL/6 mice. Supplemental Methods: Flow cytometry and statistics