Supplementary Methods and Figures 1 - 6 from The Planar Cell Polarity Pathway Drives Pathogenesis of Chronic Lymphocytic Leukemia by the Regulation of B-Lymphocyte Migration

PDF file - 695K, S. figure 1mRNA from CD19+ cells of healthy individuals. S. figure 2 Expression of Wnt-5a in the samples shown in Fig. 1 was determined by qRT-PCR. S. figure 3 Viability of primary CLL cells stimulated with the indicated compounds have been assessed by the WST1 test. S. figure 4 mRNA from MEC1 cells and from B-cells of healthy individuals was isolated and the expression of the indicated genes was analyzed by real time qRT-PCR. S. figure 5 Flow-cytometric analysis of apoptosis in patient CLL cells used for transplantation. S. Figure 6 Expression of PRICKLE1.