Supplementary Figures 1-5 from DDB2: A Novel Regulator of NF-κB and Breast Tumor Invasion

PDF - 636K, Supplementary Figure 1: DDB2 reduces migration abilities of the aggressive breast tumor MDA-MB231 cell line in wound healing-induced migration assay. Supplementary Figure 2: Knockdown of DDB2 expression induces migratory and invasive abilities in vitro of nonaggressive breast tumor T47D cell line. Supplementary Figure 3: DDB2 expression is inversely correlated with the histological SBR grade tumors. Supplementary Figure 4: DDB2 is involved in upregulation of IkBa gene in MCF-7 cells through a binding site localized in the IkBa proximal promoter. Supplementary Figure 5: NF-kB is involved in the migration and invasion abilities of MDA-MB231 and SKBR3 Neo control cells.