Supplementary Figures 1-6 from Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

Supplementary Figures 1-6 Supplementary Figure 1. PTPRN2 expression in normal and cancer tissues. Supplementary Figure 2. Validation of PTPRN2 antibodies for immunohistochemistry (IHC) and Western blot (WB) analysis. Supplementary Figure 3. MCF10A cells expressing proPTPRN2 forms larger acinar structures in Matrigel. Supplementary Figure 4. PTPRN2 is involved in IϰB/NF-ϰB and c-Jun N-terminal kinase (JNK)/AP-1 signaling pathways. Supplementary Figure 5. PTPRN2 knockdown induces apoptosis in MDA-MB-468 cells. Supplementary Figure 6. Overexpression of proPTPRN2 but not mature PTPRN2 suppresses TRAF2 phosphorylation.