Figure S4 from KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR

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摘要

Association phospho-EGFR (Y1068) and the GRB2/SOS1 complex sustained KRAS activity and led to osimertinib resistance.

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Figure S4 from &lt;i&gt;KRAS&lt;/i&gt; and &lt;i&gt;EGFR&lt;/i&gt; Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in &lt;i&gt;EGFR&lt;/i&gt;