Supplementary Figure 2 from Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism

S2. (A) Kaplan-Meier analysis of overall survival of 440 colon adenocarcinoma patients TGCA cohort. Patient group with highest quartile showed a reduced five-year survival. (B) Heatmap illustrating the correlative gene expression profile of creatine kinase enzymes (KCRU, KCRM, KCRB) and glucose transporters (GTR1, GTR3, GTR14) compared to 47 genes representing a "hypoxia signature" based on 337 CODREAD colorectal cancer patients.