Detailed Sub-study Analysis of the SECRAB Trial: Quality of Life, Cosmesis and Chemotherapy Dose Intensity

I.N. Fernando,S. Lax,S.J. Bowden,I. Ahmed, J.H. Steven, M. Churn,A.M. Brunt,R.K. Agrawal,P. Canney, A. Stevens,D.W. Rea

Clinical Oncology（2023）

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摘要

•SECRAB assessed synchronous or sequential CRT in breast cancer.•Synchronous CRT showed positive therapeutic benefit; sub-studies are reported here.•Quality of life was similar in patients receiving synchronous or sequential CRT.•Cosmesis was similar in patients receiving synchronous or sequential CRT.•Chemotherapy dose intensity was comparable between the two CRT regimens.

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关键词

Breast cancer, chemotherapy, clinical trial, cosmesis, dose intensity, quality of life, radiotherapy, secondary outcomes, SECRAB

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