A case of neutrophil blue-green inclusions in severe fever with thrombocytopenia syndrome virus infection

Wei Jiang,Ming Huang, Jiao-Hua Chen,Yang Fei,Chi Zhang

INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY(2023)

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International Journal of Laboratory HematologyEarly View LETTER TO THE EDITOR A case of neutrophil blue–green inclusions in severe fever with thrombocytopenia syndrome virus infection Wei Jiang, Wei Jiang Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People's Republic of ChinaSearch for more papers by this authorMing Huang, Ming Huang Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of ChinaSearch for more papers by this authorJiao-Hua Chen, Jiao-Hua Chen Department of Clinical Laboratory, Hubei Yangxin County People's Hospital, Huangshi, Hubei, People's Republic of ChinaSearch for more papers by this authorYang Fei, Corresponding Author Yang Fei [email protected] orcid.org/0000-0003-4976-2500 Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China Correspondence Yang Fei and Chi Zhang, Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China. Email: [email protected]; [email protected]Search for more papers by this authorChi Zhang, Corresponding Author Chi Zhang [email protected] orcid.org/0000-0002-2468-7068 Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China Correspondence Yang Fei and Chi Zhang, Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China. Email: [email protected]; [email protected]Search for more papers by this author Wei Jiang, Wei Jiang Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, People's Republic of ChinaSearch for more papers by this authorMing Huang, Ming Huang Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of ChinaSearch for more papers by this authorJiao-Hua Chen, Jiao-Hua Chen Department of Clinical Laboratory, Hubei Yangxin County People's Hospital, Huangshi, Hubei, People's Republic of ChinaSearch for more papers by this authorYang Fei, Corresponding Author Yang Fei [email protected] orcid.org/0000-0003-4976-2500 Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China Correspondence Yang Fei and Chi Zhang, Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China. Email: [email protected]; [email protected]Search for more papers by this authorChi Zhang, Corresponding Author Chi Zhang [email protected] orcid.org/0000-0002-2468-7068 Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China Correspondence Yang Fei and Chi Zhang, Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Ave, Wuhan 430030, China. Email: [email protected]; [email protected]Search for more papers by this author First published: 12 March 2023 https://doi.org/10.1111/ijlh.14056 Wei Jiang and Ming Huang are joint first authors and contributed equally to this work. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL REFERENCES 1Yu XJ, Liang MF, Zhang SY, et al. Fever with thrombocytopenia associated with a novel bunyavirus in China. N Engl J Med. 2011; 364(16): 1523- 1532. 2Harris VN, Malysz J, Smith MD. Green neutrophilic inclusions in liver disease. J Clin Pathol. 2009; 62(9): 853- 854. 3Hodgson TO, Ruskova A, Shugg CJ, McCallum VJ, Morison IM. Green neutrophil and monocyte inclusions-time to acknowledge and report. Br J Haematol. 2015; 170(2): 229- 235. 4Soos MP, Heideman C, Shumway C, Cho M, Woolf A, Kumar C. Blue-green neutrophilic inclusion bodies in the critically ill patient. Clin Case Rep. 2019; 7(6): 1249- 1252. 5NNN M, Jardim LL, Pereira LS, Rezende SM, MLP G. Blue- green cytoplasmic inclusions in neutrophils/monocytes of patients with yellow fever. Int J Lab Hematol. 2022; 44: e168- e171. 6Cantu MD, Towne WS, Emmons FN, et al. Clinical significance of blue-green neutrophil and monocyte cytoplasmic inclusions in SARS-CoV-2 positive critically ill patients. Br J Haematol. 2020; 190(2): e89- e92. 7Courville EL, Crisman S, Linden MA, Yohe S. Green neutrophilic inclusions are frequently associated with liver injury and may portend short-term mortality in critically ill patients. Lab Med. 2017 Feb; 48(1): 18- 23. 8Patel N, Hoffman CM, Goldman BI, Bentley K, Burack WR, Evans AG. Green inclusions in neutrophils and monocytes are an indicator of acute liver injury and high mortality. Acta Haematol. 2017; 138(2): 85- 90. 9Merino A, Molina A, Rodríguez-García M, et al. Detection and significance of green inclusions in peripheral blood neutrophils and monocytes. Int J Lab Hematol. 2021 Apr; 43(2): e92- e94. 10Bae HG, Drosten C, Emmerich P, et al. Analysis of two imported cases of yellow fever infection from Ivory Coast and The Gambia to Germany and Belgium. J Clin Virol. 2005; 33(4): 274- 280. 11Takahashi T, Maeda K, Suzuki T, et al. The first identification and retrospective study of severe fever with thrombocytopenia syndrome in Japan. J Infect Dis. 2014; 209(6): 816- 827. 12Fulop M, Horowitz M, Aberman A, Jaffe ER. Lactic acidosis in pulmonary edema due to left ventricular failure. Ann Intern Med. 1973; 79(2): 180- 186. Early ViewOnline Version of Record before inclusion in an issue ReferencesRelatedInformation
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thrombocytopenia,severe fever,neutrophil,infection,blue–green inclusions
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