F-18-FDG PET/CT image of tenosynovial giant cell tumor in the thoracic vertebra

Diffuse-type tenosynovial giant cell tumor (D-TSGCT) is a destructive benign tumor-like proliferative disease. Diffuse-type tenosynovial giant cell tumor rarely arises from the axial skeleton. We report a case of image findings of D-TSGCT in the thoracic vertebra. On fluorine-18-fluorodeoxyglucose (F-18-FDG) positron emission tomography/computed tomography (PET/CT) image, it presented a lytic bone destruction of 6th thoracic vertebra, vertebral processes as well as adjacent sixth rib with intense F-18-FDG uptake. Our case hints another unusual D-TSGCT image characteristic, which should be considered as a differential diagnosis when we interpret similar sign on F-18-FDG PET/CT.