479. Performance Differences in Electronic Health Record Algorithm for Bipolar Disorder by Race and Ethnicity: An Assessment From the Psychemerge Diversity Initiative

EHR-linked biobanks provide longitudinal data on diverse clinical populations that can fuel clinical, genetic, and epidemiologic research. Assigning case status is an important step in conducting psychiatric research using EHR, however it is often defined using phenotypic algorithms which have been developed from majority white individuals. Bias in assigning diagnosis codes across groups could lead to poorer performance and exacerbate disparities.