Differentiating neurosarcoidosis from multiple sclerosis using combined analysis of basic CSF parameters and MRZ reaction.

Benjamin Vlad, Stephan Neidhart,Marc Hilty,Mario Ziegler,Ilijas Jelcic

Frontiers in neurology（2023）

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摘要

Combined evaluation of basic CSF parameters and MRZ reaction is powerful in differentiating neurosarcoidosis from MS, with moderate to severe pleocytosis and Q elevation and absence of intrathecal IgG synthesis as useful rule-in parameters and positive MRZ reaction as a rule-out parameter for neurosarcoidosis.

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关键词

MRZ reaction,blood-CSF barrier dysfunction,cerebrospinal fluid,multiple sclerosis,neurosarcoidosis,oligoclonal bands,pleocytosis

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