L-Tartaric Acid Inhibits Diminazene-induced Vasorelaxation in Isolated Rat Aorta.

AIMS:The study investigated the effect of L-tartaric acid on diminazene-indiuced vasorelaxation.BACKGROUND:Diminazene is known to induce vasorelaxation through the stimulation of angiotensin-converting enzyme (ACE-2).OBJECTIVE:This work was designed to study the effect of L-tartaric acid on diminazene-induced vasorelaxation using an ex vivo approach.MATERIAL AND METHODS:In the current investigation, the inhibitory effect of L-tartaric acid on diminazene-induced relaxation.RESULTS:The results confirmed that L-tartaric acid was able to inhibit in a dose-dependent manner diminazene-induced vasorelaxation.CONCLUSION:This investigation provides important experimental evidence of the efficacy of L-tartaric acid in inhibiting diminazene-induced vasorelaxation.