The CXCR4/miR-1910-5p/MMRN2 Axis Is Involved in Corneal Neovascularization by Affecting Vascular Permeability.

Xiao Wang,Zedu Cui,Xi Chen,Qian Luo,Zihua Jiang,Xuan Liu,Yuke Huang,Jingyi Jiang,Shuilian Chen,Jin Qiu, Yan Li,Keming Yu,Jing Zhuang

Investigative ophthalmology & visual science（2023）

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摘要

Our results revealed a novel CXCR4-mediated mechanism and proved that targeting the miR-1910-5p/multimerin-2 pathway could be a promising therapeutic target for CNV.

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关键词

corneal neovascularization,neovascularization permeability,cxcr4/mir-1910-5p/mmrn2 axis

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