Digitized design and mechanical property reprogrammability of multistable origami metamaterials

•A generic tool is proposed for designing multistable origami metamaterials.•A methodology is introduced to correlate origami kinematics with material properties.•Boundaries of material properties of the synthesized metamaterials are derived.•Six categories of metamaterials with brand-new moduli programmability are revealed.•Reprogrammable moduli are experimentally verified via a 3D-printed prototype.