Role of the iNOS isoform in the cardiovascular dysfunctions of male rats with 6-OHDA-induced Parkinsonism.

Lorena de Jager,Camila Borecki Vidigal,Blenda Hyedra de Campos,Gabriela Souza Reginato,Lorena Maria Fernandes,Deborah Ariza,Carolina Matias Higashi-Mckeown,Mariana Marques Bertozzi, Fernanda Soares Rasquel de Oliveira,Waldiceu Aparecido Verri,Graziela Scalianti Ceravolo,Carlos César Crestani,Phileno Pinge-Filho,Marli Cardoso Martins-Pinge

Nitric oxide : biology and chemistry（2023）

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摘要

Thus, the set of results presented in this study suggests that part of the cardiovascular dysfunction in animals subjected to 6-OHDA Parkinsonism may be peripheral and involve the participation of endothelial iNOS.

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关键词

Blood pressure,Cardiovascular changes,Nitric oxide synthase,Parkinson's disease,S-methylisothiourea,Vascular reactivity

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