Candidate germline biomarkers of lenalidomide efficacy in mantle cell lymphoma: the Fondazione Italiana Linfomi MCL0208 trial
Blood advances(2023)
摘要
•Polymorphic alleles of either ABCB1 or VEGF genes predicted better outcome in patients with MCL receiving LEN after ASCT.•ABCB1, NCF4, GSTP1, and CRBN polymorphisms were associated with toxicity during induction and with LEN dose reductions.
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关键词
lenalidomide efficacy,mantle cell lymphoma,cell lymphoma,biomarkers
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