Isolation and Characterization of Novel Hydroxyflavone from Kigelia Africana (lam.) Benth. Fruit Ethyl Acetate Fraction Against CHO 1 and HeLa Cancer Cell Lines: in Vitro and in Silico Studies

Akingbolabo Daniel Ogunlakin,Mubo Adeola Sonibare,Oloruntoba Emmanuel Yeye,Gideon Ampoma Gyebi,Damilare IyinKristi Ayokunle,Olayemi Elizabeth Arigbede,Ibrahim M. Ibrahim,Adeshina Isaiah Odugbemi,Almas Jabeen,Syeda Farah Shah,Farzana Shaheen,Oluwafemi Adeleke Ojo

JOURNAL OF MOLECULAR STRUCTURE（2023）

引用 3|浏览30

暂无评分

摘要

This study presented the first•Scientific data on the anti-proliferative activity of a novel hydroxyflavone isolated for the first time from Kigelia africana fruit, against cervical cancer (HeLa) and tumorigenic (CHO-1) cells.•Understanding the molecular interaction of the compound against p53 protein target.

查看译文

关键词

Kigelia africana,Phytochemistry,Flavonoid,Anti-proliferation,Molecular docking,Molecular dynamic simulation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要